Bulletin of Pure & Applied Sciences- Zoology
  • Year: 2011
  • Volume: 30a
  • Issue: 1

Androgen insensitivity syndrome (testicular feminization): First case report from Jammu & Kashmir, India

  • Author:
  • Shalu Sharma1, Wahied Khawar Balwan2,
  • Total Page Count: 7
  • Page Number: 25 to 31

1Department of Zoology, University of Jammu, Jammu-180006, India

2Department of Zoology, Govt. Degree College Doda, Doda City-182202, India

*Corresponding Author: Dr. Wahied Khawar Balwan, Asstt. Professor, Department of Zoology, Govt. Degree College, Doda, Doda City, Dist. Doda- 182202, J &K, India. E-mail: Wahied_kb@yahoo.co.in

Online published on 22 February, 2013.

Abstract

The Androgen insensitivity (testicular feminization) syndrome is an X-linked recessive disorder where affected males despite having 46, XY karyotype, have some features of a female. 46, XY karyotype leads to the differentiation of testes ‘in utero’, but a defect in the gene coding for the androgen receptor results in complete insensitivity to circulating androgens. It is the most common cause for male pseudohermaphroditism; therefore, the case becomes important from genetic and medical viewpoint.

Keywords

Testicular Feminization, Androgen Insensitivity