Anti-hypertensive and anti-microbial activity of protein hydrolysate obtained from seven edible insects

The bioactive peptides derived from plants and insects have increased contemplation for their function in preventing numerous diseases, including, cardiovascular diseases and microbial infection. Edible insects comprise rich contents of bioactive peptides, which are recognized as antioxidant, anti-inflammatory, anti-diabetic, and anti-obesity properties. The current investigation was aimed to assess the antihypertensive and anti-microbial properties of protein hydrolysates obtained from renowned seven edible insects’ after simulated gastrointestinal enzymatic digestion. Antihypertensive efficiency was determined by the inhibition of digestive enzymes viz., ACE inhibitory activity. Three active protein hydrolysate extracts (1.25, 2.5, and 5mg/dl) were selected based on the IC50 values and all tested extracts inhibited those enzyme activities in a dose-respective manner. Antimicrobial activity was analyzed by the Kirby-Bauer test using nine strains of Gram- positive/negative bacteria with Candida albicans. Based on the present study, we found the outcome of antihypertensive and antimicrobial activityof the protein hydrolysate obtained from the seven edible insects.