Bulletin of Pure & Applied Sciences- Zoology
  • Year: 2020
  • Volume: 39a
  • Issue: 2

Cuticular hydrocarbon variation in rotenone induced and transgenically created parkinson’s disease (PD) flies of Drosophila melanogaster

  • Author:
  • Ali Hatami Dehnow1, Mysore Siddaiah Krishna2,*
  • Total Page Count: 7
  • Published Online: Feb 6, 2021
  • Page Number: 281 to 287

1Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore, 560006, Karnataka, India

2Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore, 560006, Karnataka, India

*Corresponding Author: Dr. M.S. Krishna, Drosophila Stock Centre, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore, 560006, Karnataka, India E-mail: drosokrish@gmail.com

Abstract

Drosophila melanogaster use cuticular hydrocarbons (CHCs) to identify species, gender, and reproductive status. Diet and environmental factors also influence the cuticular hydrocarbon variation. Current study examines cuticular hydrocarbons variations in rotenone-induced flies and transgenically created Parkinson’s disease (PD) flies. Eleven compounds were found in control and experimental flies of Drosophila melanogaster, however, their concentration varied significantly between control and experimental flies, which suggests that influence of rotenone, and creatine supplement on cuticular hydrocarbon in Drosophila melanogaster.

Keywords

Parkinson disease, Rotenone, Cuticular hydrocarbon, Creatine supplement, Drosophila melanogaster transgenic PD flies