Bio Science Research Bulletin
  • Year: 2013
  • Volume: 29
  • Issue: 2

Deterioration of CD4 T-cells in HIV/AIDS individuals infected with pathogenic Microsporidium in Benue state, Nigeria.

  • Author:
  • AB Yako1,, JA Ajayi1, JK Makpo1, KI Auta2, JB Yako3, HA Banyigyi1, SM Ojo2
  • Total Page Count: 8
  • Page Number: 57 to 64

1Faculty of Natural and Applied Sciences, Department of Biological Sciences, PMB 1022, Nasarawa State University, Keffi, Nigeria

2Department of Basic and Applied Sciences, Federal Polytechnic, Nasarawa, Nasarawa State, Nigeria

3Police Staff Collage Clinic, Yakubu Gowon Way, Jos, Plateau State, Nigeria

*Correspondence: Yako AB, Department of Biological Sciences, Nasarawa State University, PMB 1022, Keffi, Nigeria. E:-mail: andyako66@yahoo.com

Online published on 23 January, 2014.

Abstract

Preliminary survey in Benue State shows that 96 HIV/AIDS individuals were infected with pathogenic microsporidium. 966, 42 (4.3%) males CD4 T-cells count were <335 cell/μl, and in the female category 1042, 54 (5.2%) CD4 T-cells were <320 cell/μl at the first CD4 count. The strain of pathogenic microsporidium in HIV/AIDS individuals was observed as a leading cause of diarrhea, and a fall in the CD4 T-cells count after 90 days of re-evaluation. Among the age group of 30–39 years, the CD4 cells count gradually deteriorate to <200 cell/μl indicating high risk to acquired immune deficiency syndrome (AIDS) and opportunistic infections. However, there was a significant relationship among sexes given that, Z=1.039<±1.96 in other words, microsporidium was solely depended on age which shows no significant relationship among the age groups (x2=7.815>0.05).

Keywords

HIV/AIDS individuals, Strain of pathogenic microsporidium, Acquired immune deficiency syndrome (AIDS)