Computational Approaches for Drug Designing

Computational biology is an emerging meadow for designing of new target specific drugs. These approaches rely on the computer aided mo-lecular alignments between the "receptor" and "ligand". The probable molecular receptor of a drug can be designed through the homology modelling, in which known homologues of unknown receptor are used as template. Thereafter, docking studies are required to identify and visualize the probable binding functionalities involved in molecular inter-actions. In this short review, we explore the use of various computations resources for structure-based drug designing.