Department of Molecular Biology and Genetic Engineering, Sardar Vallabhbhai Patel University of Agriculture & Technology, Meerut-250110, U.P.
*Corresponding author E-mail: -sguptambge@yahoo.com
Online published on 6 July, 2016.
Type 2 diabetes is a chronic metabolic disorder worldwide. One of the novel approaches in the management of type 2 diabetes consist of orally administration of DPP IV inhibitors. DPP IV is a serine protease implicated in the inactivation of the incretin hormone. The aim of the present study was to evaluate the potential of the foxtail millet seed storage proteins to serve as precursor of the DPP IV inhibitors by using in-silico approach. A total 9 foxtail millet seed storage proteins were used in this study. Proteins SP-3 and SP-7 has maximum no. bioactive peptide sequences of DPP IV inhibitors. This study concludes that foxtail millet can be used as functional food and it should be include in diet of diabetic patients.
Protein, Foxtail millet Seed storage Proteins, Diabetes
