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Bioinformatics is the application of computer technology to the management of biological information. Computers are used to gather, store, analyze and integrate biological and genetic information. Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, information and computation theory, software engineering, data mining, image processing, modeling and simulation, signal processing, discrete mathematics, control and system theory, circuit theory, and statistics. The need for Bioinformatics capabilities has been precipitated by the explosion of publicly available genomic information resulting from the Human Genome Project. Bioinformatics was applied in the creation and maintenance of a database to store biological information at the beginning of the “genomic revolution”, such as nucleotide sequences and amino acid sequences. Genome annotation, sequence analysis, evolutionary biology and biodiversity are the major focus of research in bioinformatics.
annotation, Genome, mass spectrometry, mutation, cancer