Current Neurobiology
  • Year: 2012
  • Volume: 3
  • Issue: 2

Laminar cytoarchitecture of cerebral cortex in Cav2.1 mutant, rolling mouse Nagoya

  • Author:
  • Miwa Horiuchi-Hirose1, Kazuhiko Sawada2,, Yoshihiro Fukui3
  • Total Page Count: 5
  • Page Number: 85 to 89

1Department of Nutrition, Faculty of Medical and Health Sciences, Tsukuba International University, Tsuchiura, Ibaraki, Japan

2Department of Physical Therapy, Faculty of Medical and Health Sciences, Tsukuba International University, Tsuchiura, Ibaraki, Japan

3Department of Anatomy and Developmental Neurobiology, University of Tokushima Graduate School Institute of Health Biosciences, Tokushima, Japan

*Correspondence to: K. Sawada, Department of Physical Therapy, Faculty of Medical and Health Sciences, Tsukuba International University, 6-8-33 Manabe, Tsuchiura, Ibaraki 300–0051 Japan

Online published on 26 February, 2013.

Abstract

The present study quantitatively examined the laminarcytoarchitecture of functional cortical areas of the cerebrum in Cav2.1 mutant, rolling mouse Nagoya. Brain weights were not significantly different between rolling and wild-type mice. Kl üver Barrera’s staining of the cerebral cortex revealed no obvious changes in ctytoarchitecture of three functional cortical areas, i.e., primary motor (M1), somatosensory (S1) and primary visual (V1) areas,in rolling mice.The cortical thickness and the thickness of the cortical layers (I-VI) of those three areas were not significantly different between rolling and wild-type mice.The results suggest that the cytoarchitectural organization in the functional cortical areas of the cerebral cortex is not altered by a Cav2.1 gene mutation.