1Scientific and Technical Research Center in Physicochemical Analysis, BP 384, Bou-Ismail Industrial Zone, RP 42004, Tipaza, Algeria
2Faculty of Science and Technology, Mohamed Cherif Messaadia University, B.P 1553, Souk-Ahras, Algeria
*Corresponding Author's E-mail: samira.djefaflia@yahoo.com
Online published on 21 July, 2020.
[Znic oxide is a commonly occurring mineral in soils. Soil is also ultimate sink for engineered nano-ZnO. In view of Covid-19 Pandemic and that nano-ZnO is reported to have damaged or destroyed genetic make-ups in living cells in plants, this paper has been commissioned to explore the potential use of nano-ZnO to control the virus by destroying its genetic structure - Chief Editor]
In this article, by using the Forcite module of Materials Studio software, we studied the interactions between ZnO as a magic material because of its versatile applications, where the Zinc oxide NPs are used in biomedicine like biomedical imaging, drug delivery, gene delivery, and bio sensing potential, On the other hand, nano-ZnO is reported to have damaged or destroyed genetic make-ups in living cells in plants; and Alanine because it is one of the 20 amino acids mainly present in the peptide chains of proteins, and because of its exceptional properties, in the goal of knowing their interactions to estimate the interactions of ZnO with the coronavirus. The results of geometric optimization showed that there are very strong interactions between ZnO and Alanine where the structure of ZnO got distorted by releasing Zn2+ ions. The release of Zn2+ ions in the middle of proteins Leads to the Zinc fingers. The abundance of Zn2+ ions in the medium of proteins leads to the abundance of proteins of Zinc fingers, which have a lot of influence on the proteins and its structures apart from a few more advantages. We conclude that the interactions of ZnO with proteins could find a way to destroy viruses, especially novel coronavirus (Covid-19).
Alanine, Coronavirus, nanotechnology, nano-zinc, Protein Data Bank, zinc fingers, ZnO nanoparticles