Development of NEUROAchFET circuit for Patients Having Neurological Disorder

Many people across the world suffer from Parkinson's, Alzheimer's and other neurological disease. The patients having neurological disorder cannot transmit signals due to inability of detecting Acetylcholine (a neurotransmitter enzyme). An acetylcholine field effect transistor (AchFET) has been fabricated and used for detecting neuronal signals in this paper. AchFET is actually an enzyme modified field effect transistor (ENFET) which uses the concept of ion sensitive field effect transistor (ISFET).The circuit used here is simple and compatible to biological environment. The AchFET when used in the electronic circuit reproduces action potential same as obtained by experimental data published earlier. Although there are various models developed, but none of them takes into account the synaptic transmission. This model can be helpful for synaptic transmission for patients having problem in acetylcholine detection and the circuit has been named as the NEUROAchFET circuit.