CURRENT TRENDS IN BIOTECHNOLOGY AND PHARMACY
Open Access
SCOPUS
  • Year: 2020
  • Volume: 14
  • Issue: 4

Unlocking the therapeutic potential of Syzygium cumini Seeds extract

  • Author:
  • N Utharalakshmi, S Gayathri, S Hansika, G Narendrakumar*
  • Total Page Count: 12
  • Page Number: 403 to 414

Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and technology, Chennai-600 119, Tamilnadu, India

*Corresponding author: gnaren22@gmail.com

Online published on 27 May, 2021.

Abstract

This work provided initial evidence that the methanol and ethanol extract of Syzygiumcumini seeds polyphenol compounds are separated. The major polyphenolic compounds are determined and its derivatives posses strong amylase and tryosinase inhibitory activities with IC50 values more than 50μg/ml for amylase and more than 80μg/ml for tryosinase respectively. Such half maximal inhibitory concentration (IC50) values substantiate to manage diabetes and neuroprotective effects in patients to minimize the secondary complications associated with diabetes and melanogenesis.

Keywords

Syzygium cumini, Tyrosinase, Amylase activity, Anti-diabetic