Microwave Synthesis of some new Quinazolinone Formazans for theirAntimicrobial andAntihelminthicActivities

Halogenated hetrocyclic compounds have a wide range of pharmacological activities such as antimicrobial, analgesic, anti-inflammatory and hypoglycemic activities. In the present study 1-halo substituted phenyl-3-halo substituted phenyl-4[benzamido-(2-methyl-3-quinazoline)-4-one] formazans were synthesized by microwave irradiation and conventional heating. Synthesized compounds were screened for antimicrobial and antihelminthic activities. The title compounds were characterized by FTIR, ¹HNMR and mass spectroscopic analysis. Selected compounds possess significant antimicrobial and antihelminthic activities. The compounds were synthesized by microwave irradiation in 1.5 to 6 minutes.