1Department of Pharmacy, Acharya Nagarjuna University, Guntur – 521250, A.P., India.
2University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, A.P., India.
3Centre for Pharmaceutical Sciences, J N T University, Hyderabad – 500085.
*For Correspondence - srinath_n2k@rediffmail.com.
A series of some new chalcones were synthesized by Claisen-Schmidt condensation of 3'-methyl-4'-hydroxyacetophenone with various substituted aromatic/heteroaromatic aldehydes in the presence of alkali. The resulting chalcones were characterized by IR, 1H NMR and Elemental analysis. These chalcones were evaluated for their anti-inflammatory activity and some of them exhibited significant activity when compared with the standard.
Chalcones, Synthesis, Anti-inflammatory activity
