1Department of Biochemistry & Molecular Biology, Faculty of Pharmacy, Cyprus International University, Mersin Yolu, Nicosia, Cyprus
2Department of Biochemistry, Faculty of Pharmacy, Marmara University, Istanbul
3Department of Heart Surgery, School of Medicine, Marmara University, Istanbul
4Department of Clinical Biochemistry, Memorial Hospital Group, Istanbul, Turkey
5Florida Hospital Medical Center, Orlando, FL-32804, USA
*For Correspondence - stetik@ciu.edu.tr
Online published on 29 April, 2013.
The Thrombelastograph™ (TEG) provides a global assessment of blood coagulation. The study aim was to evaluate the dynamic haemostatic parameters utilizing TEG in blood specimens of hyperlipidemic patients (n=22) and healthy donors (n=15) before and 30 min after the angiography. Such TEG parameters as: reaction time (R, min), clot formation time (K, min), fibrinogen activity (Angle, degree), clotting maximum amplitude (MA, mm), and clotting index (CI) were quantitated. The patients’ values before vs. after the angioplasty were: R = 4.74±1.59 vs. 3.36±0.89 min (5.48±1.39 min for control), K = 2.77±2.45 vs. 1.75±0.95 min (1.57±0.24 min for control), Angle = 64.38±11.21 vs. 69.72±8.22 degree (67.13±6.67 degree for control), MA = 52.2±16.94 vs. 57.84±9.46 mm (59.97±4.73 mm for control), and CI = 0.31±2.59 vs. 1.71±2.07 (0.22±2.14 for control). It is clear that the risk ratio was lowered in patients after the angiography where increased haemostatic defects were detected before the angiography.
Haemostatic system, Angiography, Thrombelastography, Coronary artery bypass graft
