Effect of curcuma longa on brewer's yeast induced pyrexia in albino rats

Alcoholic extract of Curcuma longa L. (Haldi) was evaluated for its antipyretic activity on Brewer's yeast induced pyrexia in albino rats. The alcoholic extract of Curcuma longa (600 mg/kg body weight, intraperitoneally), produces change in rectal temperature from 39.38°C to 39.68, 39.4 and 39.3°C at 24th, 25th, 26th and 27th hour of yeast administration and at zero, first, second and third hour of Curcuma longa administration, respectively. The changes were significant at second and third hour of treatment as compared to control. The C.longa was found to be less potent than standard antipyretic drug Paracetamol (100 mg/kg b.w., I/P).