Department of Veterinary Microbiology, Dr. G.C. Negi College of Veterinary & Animal Sciences, CSKHPKV, Palampur, H.P. E-mail: sverma8@yahoo.co.uk
Online published on 30 January, 2014.
Particularly found in remote areas of the state, the present study on Pahari cattle vis-a-vis Jersey was focused on studying the immunological and immunogenetic traits of these animals as they were believed to be highly adaptogenic and have better innate and adaptive immune responses to fight infectious diseases. The immunological parameters studied included the humoral and cell mediated immune (CMI) responses while in the immunogenetic parameters the analysis was focused on BoLADRB, TLRs and beta casein. Besides, the antimicrobial properties of cow urine were also studied. The highlights are summarized as under:
Neutrophils of Pahari cow were more phagocytic in comparison to Jersey cow.
Pahari cattle responded by inducing greater amount of antibodies to standard antigens as measured by ELISA.
Greater increase in skin fold thickness in Pahari cattle as opposed to Jersey when DNFB was used as antigen indicates better CMI response.
Hematologically and physiologically the study has revealed that Pahari cattle which have been brought from their native place to the place of study have the blood and physiological profile comparable to that of those cattle which are being reared at their native place.
BoLA-DRB loci did not reveal mutation (s) that have been associated with susceptibility to mastitis.
SNP profiling of TLR-2 have shown that a mutation at nucleotide position 356 is unique in these animals & could have potential role in offering added advantage to recognize PAMP.
Very high frequency of beta casein A2 genotype was recorded for Pahari cow in comparison to Jersey.
Pahari cow urine distillate has bioenhancer properties against both gram positive and gram negative bacteria with bioenhancing properties varying from 13% to 63%.
