Indian Internet Journal of Forensic Medicine & Toxicology
  • Year: 2017
  • Volume: 15
  • Issue: 1

Giant cell formation in rat hepatocytes under stress of cypermethrin and beta-cyfluthrin

1Department of Zoology, Pandit Sant Ram Government Degree College, Baijnath-176125, Himachal Pradesh, India

2Department of Zoology, School of Life Sciences, Dr. B.R. Ambedkar University, Khandari Campus, Agra-282002, Uttar Pradesh, India

*Corresponding author email id: bantu.sls@gmail.com

Abstract

Pyrethroids are greatly in use these days therefore can contaminate ecosystem and living forms therein. Present investigation reveals the toxic potential of two type-II pyrethroids, cypermethrin and beta-cyfluthrin at the level of giant cell formation through histological examination in liver of albino rats. It has been observed that both these experimental compounds cause giant cell formation in the liver of treated animals with beta-cyfluthrin having an edge over cypermethrin, probably due to difference in their chemical structures.

Keywords

Albino rats, Beta-cyfluthrin, Cypermethrin, Giant cells, Liver, Pyrethroids, Toxicity