Indian Journal of Applied Basic Medical Sciences
Open Access
  • Year: 2013
  • Volume: 15b
  • Issue: 21

Association of ABO blood groups with coronary artery disease in Gujarati population

  • Author:
  • Dharmendra M. Dodiya1,, Vanita Panchal2, Gaurang Patel3, Maulik Nayak4
  • Total Page Count: 7
  • Page Number: 66 to 72

1Assistant professor, Dep. of Physiology, GMERS Medical College, Sola, Ahmedabad

2Assistant Professor, Dep. of Physiology, GMERS Medical College, sola, Abad

3Assistant Professor, Dep. of Forensic Medicine, GMERS Medical College, sola, Abad

4Assistant Professor, Dep. of Biochemistry, GMERS Medical College, sola, Abad

*Corresponding Author- Assistant professor, Dep. of Physiology, GMERS Medical College, Sola, Ahmedabad

Online published on 22 May, 2014.

Abstract

Coronary artery disease (CAD) rates vary 10-fold among populations. The CAD rates among overseas Asian Indians worldwide are 50% to 400% higher than people of other ethnic origin irrespective of gender, religion, or social class. Due to inadequate information in the local population, the current study was conducted to find the association between ABO blood group system and coronary artery disease, so as to help in developing preventive strategies. A cross sectional study was conducted on 254 patients of coronary artery disease belonging to Guajarati community. Odds ratio was used to determine the relative risk of CAD association with ABO blood group system. A significant association was observed between CAD and ABO blood group system. Until now there is little study has undergone to find out association of ABO blood group with CAD (coronary artery disease) and different subgroup of patients of CAD having DM & HT, NON-DM & NON-HT, DM but NON-HT, HT but NON-DM.

To evaluate and find out association of ABO blood group on patients of coronary artery disease in Gujarati population.

we observed that overall prevalence of ABO blood group in Local population was B blood group (33.93%), O (31.36%), A (24.39%) & AB (10.30%), while prevalence of ABO blood group in diseased people (people suffering from CAD) was O blood group (35.03%), B 30.70%), A (25.19%), AB (9.0%) different. Further, significant difference was noted between different subgroup of CAD.

Persons having blood group O and A have high relative risk of coronary artery disease as compared to persons having blood group B and AB. Early onset of CAD was seen in blood group A as compared to other blood groups.

Keywords

CAD - Coronary artery disease, CABG – coronary artery bypass grafting, CAG – coronary angiography, ABO blood group