Indian Journal of Applied Basic Medical Sciences
Open Access
  • Year: 2014
  • Volume: 16b
  • Issue: 23

Analgesic & anesthetic property of levobupivacaine compared with bupivacaine in patients undergoing a supra- clavicular brachial plexus block

  • Author:
  • Charu J Pandya1, Gauri M Panjabi2, Chirag Baranda3
  • Total Page Count: 5
  • Page Number: 5 to 9

1Associate professor, Smt. S.C.L Smt. SCL. Gen Hospital, Saraspur, Ahmedabad

2Assistant professor, Smt. S.C.L Smt. SCL. Gen Hospital, Saraspur, Ahmedabad

33rd year, resident, Smt. S.C.L Smt. SCL. Gen Hospital, Saraspur, Ahmedabad

Online published on 21 September, 2015.

Abstract

Single injection of supraclavicular brachial plexus block is an effective anesthetic; however it is limited by the duration of action of local anesthetic. Bupivacaine is a long-acting local anesthetic which has been reported to be associated with slower onset time for nerve blockade.

The present study was conducted in random 60 patients posted for upper limb surgery having ASA grade 1 and 2 physical status. The patients were randomly allotted into two groups each having 30 patients. Group R- inj. Levobupivacaine 0.5% 0.8 ml/kg Group B- inj. Bupivacaine 0.5% 0.8 ml/kg. And the effects were assessed.

There was significant difference in duration of sensory block (<0.05), and analgesia (<0.05) in both the groups. The average duration of sensory block was 630±95.22 minutes in L Bupivacaine group whereas it was 525±.8 minutes in Bupivacaine group which was significant statistically. The average duration of motor blockade was 520±20, minutes in L-Bupivacaine group whereas it was 612±89.41 minutes in Bupivacaine group which was not significant statistically (p<0.05). The average duration of analgesia was 781 minutes in L bupivacaine group as compared to 622 minutes in Bupivacaine group which was statistically significant.

Levobupivacaine is a long acting local anesthetic with a clinical profile similar to that of bupivacaine. In an individual patient, the clinical anesthetic effect from the drug is similar to that of bupivacaine. The better safety profile of levobupivacaine confers an advantage over its racemic parent, Bupivacaine.