1Consultant Pathologist, Sterling hospital, Vadodara, Email: dr.devika@yahoo.com, Mobile: 9879069852
2Assistant Prof., Department of Physiology, C.U. Shah medical college, Surendranagar, Email: drkomalmakwana@gmail.com, Mobile: 8128652118
3Associate professor, Department of Pathology, G.M.C., Bhavnagar
4Assistant professor, Department of Pathology, G.M.C., Bhavnagar
Online published on 21 September, 2015.
FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) is a relatively simple, reliable, atraumatic, economical and complication free technique for the evaluation of mass lesions. In this study we want to correlate the cytological findings of breast lumps with their histomorphological diagnosis on excision.
To evaluate the usefulness of Fine needle aspiration cytology in diagnosis of palpable breast lumps. To correlate the cytological findings of breast lumps with their histomorphological diagnosis on excision.
This is retrospective study of FNAC of breast done in pathology department of Government medical college Bhavnagar from July 2008 to December 2010. The patients (172 females and 3 males) presented with clinically palpable breast lumps were referred for FNAC. Their ages ranged from 15 to 80 years. In 6 cases in which there was associated nipple discharge, cytological smears from the nipple discharge were prepared. Cytohistological correlation was done in 100 cases subjected to subsequent histopathology. Aspiration was done with 5 ml disposable syringe fitted with 23 gauge needle and material spread on glass slides was air dried for staining with May Grunwald Giemsa stain and wet fixed in 95% ethylalcohol and stained with Papanicoloau Stain and Hematoxylene and eosine stain.
The present study was carried out in 175 patients, out of total 175 breast aspirations 113 were benign, 55 malignant lesions and rest 7 were suspicious of malignancy. Histological correlation was done in 100 cases. Sensitivity of study was 96% and specificity for malignancy was 100%. Positive predictive value was 100% and negative predictive value was 93.1%.
This study has concluded that the fine needle aspiration cytology of breast lumps is simple, cheap, quick, reliable method to diagnose the breast lesions. Breast cytology is an effective and rapid method of diagnosis of breast diseases. It helps in deciding which patient needs an early open biopsy and when it is performed by an expert pathologist, the diagnostic accuracy of FNAC is very high.
FNAC, Breast lumps, Open biopsy
