Salivary duct carcinoma is a distinctive primary neoplasm of the major salivary gland characterized by aggressive behaviour with early metastasis, local recurrence and significant mortality. We report a 50 year old male with parotid swelling whose FNAC was suggestive of a differential diagnosis of Salivary Duct Carcinoma or a Mucoepidermoid carcinoma, he underwent parotidectomy and later, on routine histopathology, the swelling was reported as a salivary duct carcinoma, confirmed via immunohistochemistry. Given the relative low occurrence and known difficulty in making an accurate diagnosis using fine needle aspiration cytology, the possibility of salivary duct carcinoma in the appropriate clinical setting of elderly patients with parotid mass and facial palsy should be seriously considered.
