Indian Journal of Applied Basic Medical Sciences
Open Access
  • Year: 2015
  • Volume: 17b
  • Issue: 25

Comparison of epidural butorphanol versus fentanyl with bupivacaine for post operative analgesia in lower abdominal and lower Limb Surgeries

  • Author:
  • Rupal J Shah1, Manisha S Kapdi2, Alpesh Prajapati3
  • Total Page Count: 12
  • Page Number: 48 to 59

1Asst. Professor Anaesthesia-NHL medical college, Ahmedabad, pin 380006

2Associate Professor Anaesthesia-AMC MET medical college, Ahmedabad, pin 380008

3Ex. Resident, Anaesthesia-NHL - NHL medical college, Ahmedabad, pin 380006

Online published on 21 September, 2015.

Abstract

This prospective randomized controlled clinical comparative study entitled “COMPARISON OF EPIDURAL BUPIVACAINE AND BUTORPHANOL VERSUS EPIDURAL BUPIVACAINE AND FENTANYL FOR POST OPERATIVE ANALGESIA IN LOWER ABDOMINAL AND LOWER LIMB SURGERIES” was conducted in 50 patients of either sex, aged between 18- 60 years of ASA grade É and ÉÉ admitted for elective surgeries during 2011–2013.

Written informed consent was taken and pre-anesthetic evaluation was done. Epidural catheter was inserted and all patients were given spinal anesthesia using 0.5% hyperbaric Bupivacaine (15mg). In the postoperative period, when patient complained of pain, intensity of pain was assessed using Visual analog scale and when VAS score was 4 or more they received epidural Bupivacaine (0.5%) 2.5 ml and Butorphanol 2mg (group BB) or Bupivacaine (0.5%) 2.5 ml and Fentanyl 50µg (group BF) diluted to 10ml with NS. Parameters were observed were; Onset of analgesia, Duration of analgesia Cardio- respiratory effects and adverse effects.

(age, sex weight hemodynamics and ASA grade) was comparable in both groups.

Mean onset of analgesia was rapid (4.5+1.06S.D) minutes) in group BF when compared to group BB (6+1.32 (S.D) minutes. This was clinically and statistically significant (p< 0.001).

Duration of analgesia was longer in group BB which ranged from 300–550 minutes with a mean of 410+50.29 minutes compared to group BF which ranged from 250–450 minutes with a mean of 330+39.32 minutes. This was clinically and statistically significant (p< 0.001).

There was no significant difference in heart rate, blood pressure and respiratory rate monitored at regular intervals for 12 hours postoperatively between the two study groups.

Sedation was the main side effect in group BB. Frequency of pruritis and nausea-vomiting was more in group BF. Hypotension and respiratory depression were not found statistically significant in either group.

All patients were monitored for 12 hours postoperatively for any untoward effects.