A Novel Synthesis of New Platinum(II) Complexes With N-(Substituted Aryl or Benzyl)-Г-Mercaptobutyramides by Using Phase Transfer Catalysis

The synthesis of platinum phosphine complexes containing N-(substituted aryl or benzyl)-γ- mercaptobutyramides by using phase transfer catalysis are reported. Complexes of the form [{4X-C₆H₄NHCO(CH₂)₃S}₂Pt(PMe₂Ph)₂], where X = OCH₃, CH₃, Cl, benzyl, have been synthesized by the reaction of cis-dichlorobis (dimethylphenylphosphine) platinum(II) with the corresponding N-(substituted aryl or benzyl)-γ-mercaptobutyramide in a two phase system of water and chloroform in the presence of benzyl triphenyl phosphonium chloride. The complexes were characterized by elemental analysis, i.r, and ¹H, and ¹³C NMR spectroscopy.