International Journal of Applied Chemistry

  • Year: 2007
  • Volume: 3
  • Issue: 2

A study of probing the mechanism of acylation reactions and fries rearrangement by polyphosphoric acid (PPA)

  • Author:
  • Mostafa Gholizadeh
  • Total Page Count: 6
  • Page Number: 139 to 144

Chemistry Department, Sabzevar Tarbiat Moallem University, Sabzevar, Iran. E-mail: m_gholizadeh@sttu.ac.ir

Abstract

P2O5/H3PO4 (PPA) was found to be an efficient new reagent for probing the mechanism of acylation reactions and Fries rearrangement of acyloxy benzene derivatives and also the direct acylation reactions of phenol derivatives with Carboxylic acids. The reactions proceeded smoothly in the presence of PPA and are highly selective for the preparation of the ortho isomers of hydroxyaryl ketones.

In the same way we have investigated the effects of ortho, meta and para substituents on the acylation reactions of benzoic acid derivatives and also Fries rearrangement in PPA.

Keywords

Polyphosphoric acid (PPA), Acylation reactions, Fries rearrangement, Hydroxyaryl Ketones, Phenol derivatives