1Department of Science Education, University of Education, P. O. Box 25, Winneba, Ghana.
2Department of Chemistry and Forensic Science, University of Bradford, Richmond Road, West Yorkshire, BD7 1DP, United Kingdom.
3Department of Biology, Liverpool polytechnique, Liverpool, L3 3AF United Kingdom.
Rosellinia arcuata a member of the Xylariacaea, which was static cultured, produced cyclic compounds; 6-(1-hydroxypent-1-yl)-4-methoxytetrahydro2H-pyran-2-one (pestalotin), 4-me thoxy-6-pentnoyl-5,6-dihydro-2-pyran-2one (didehydropestalotin), 3-(3-methylbuta-1,3-dien-1-ylidene)-7oxabicyclo[4.1.0]heptane-2,5-diol (allenic epoxycyclohexane) and 8-hydroxy 3-methyl-1-oxo-3,4-dihydro-1H-isochromen-5-carboxylic acid (5carboxymellein). The similarity between Pestalotin and Didehydopestalotin suggest they might have been produced through the same biosynthertic pathway. The stereochemistry of allenic epoxycyclohexane has been discussed.
Secondary metabolites, Rosellinia arcuata, NMR spectroscopy
