International Journal of Applied Environmental Sciences

  • Year: 2010
  • Volume: 5
  • Issue: 1

Cytochalasins from Static Cultures of Rosellinia Arcuata

  • Author:
  • E.K. Oppong1, R.L. Edwards2, D.J. Maitland2, A.J.S. Whalley3, Y. Ameyaw1
  • Total Page Count: 9
  • DOI:
  • Page Number: 77 to 85

1Dept. of Science Education, University of Education, P. O. Box 25, Winneba, Ghana.

2Dept. of Chemistry and Forensic Science, University of Bradford, Richmond Road, West Yorkshire, BD7 1DP. United Kingdom.

3Dept. of Biology, Liverpool Polytechnique, Liverpool, L3 3AF, United Kingdom.

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Abstract

Static cultures of Rosellinia arcuata were extracted with ethyl acetate to give intimate mixtures of four cytochalasins. Isolation, purification and characterisation of the cytochalasins afforded cytochalasin C, 19,20epoxycytochalasin C and a new cytochalasin, engleromycin acetate. Soxhlets extraction of the pulverized mycelium gave pure 19,20-epoxycytochalasin C, from which another new cytochalasin 19,20-dihydroxycytochalasin C was synthesized.

Keywords

Cytochalasin, Rosellinia arcuata, NMR Spectroscopy