The present study was conducted on large intestine of six adult goats. The large intestine comprised three parts i.e. caecum, colon and rectum. Four types of layers are present throughout large intestine, these are tunica mucosa, tela submucosa, tunica muscularis and tunica serosa. Tunica mucosa contained simple columnar epithelium with striated border, lamina propria with intestinal glands, lymphatic nodules and lamina muscularis. Intestinal glands are lined by tall columnar cells and exhibited secretory activity with bleblack appearance in the lumen and mostly serous secreting. Goblet cells are highest in the rectum. Lymphatic nodules in colon show lacteal duct and present at the base region of tunica mucosa.
