Relationship between plasma haptoglobin, monocyte toll like receptor 4 expression with growth and the effect of supplementation of fermented yeast culture on low body weight crossbred calves

The relationship between circulating Haptoglobin, Toll like receptor 4 (TLR 4) expression and growth of post weaned low body weight crossbred female calves with supplementation of fermented yeast culture. The expression of TLR 4 receptor and plasma Haptoglobin concentration may act as indicators for post weaning stress and subclinical infection. At nine months of age, Karan Fries calves were grouped in to normal (HBW) and low body weight (LBW) calves fermented yeast culture (Saccharomyces cerevisiae) was supplemented @ 300g/ quintal of concentrate mixture for feeding of low body weight. The calves were offered wheat straw and green fodder to meet their nutritional requirements. The concentration of plasma Haptoglobin (Hp) was observed to be negatively correlated with body weight Expression of TLR 4 in monocytes was down regulated in low body weight group female crosbred KF calves (LBW) when compared with normal growing calves (HBW). Fermented yeast culture supplementation improved the average daily gain, metabolic body weight (BW^0.75) and expression of TLR 4 and decreased concentration of plasma Haptoglobin in LBW group calves.