Oxidative stress biomarkers in cross bred cows affected with foot and mouth disease

The aim of the study was to measure the oxidative stress biomarkers and also elucidate the hematological and biochemical picture of cross bred cow with foot and mouth disease From the study it was observed that among the oxidative strees biomarkers, superoxidase dismutase, glucose-6-phosphatase, ascorbic acid and uric acid showed a significant (P< 0.05) decrease in th FMD affected animals. Among the hematological and biochemical parameters, the RBC count, serum total protein, albumin, cholesterol, urea, BUN, and calcium showed a highly significant (P< 0.01) decrease in the FMD affected animals in comparison to the healthy animals but indirect serum bilirubin and AST activity increased significantly (P< 0.05) in the FMD affected animals. These results demonstrate that the cows with FMD were under oxidative stress and there was a significant change in some of the blood metabolites. Thus, during FMD the antioxidant vitamins (eg Vit A, Vit C, Vit E) would be beneficial for the antioxidant defense system of the animals.