Immunological profiles of lactating and mastitis crossbred cattle

In order to assess the immune profiles of lactating and mastitis crossbred cows, blood samples were collected weekly for one month from early, mid and late lactating cows and once from clinical and subclinical mastitis cows. Immune markers nitric oxide, tumor necrosis factor α and immunoglobulin G were estimated in blood plasma. A concurrent significant (P<0.05) fall in IgG concentration was noted in clinical mastitis cows and was highest during mid lactation in lactating cows. The clinical and subclinical mastitis cows had significantly (P<0.05) high levels of TNF-α and were non-detectable in lactating cows. Plasma NO level exhibited a massive rise (P<0.05) in mastitis cows (clinical and subclinical), the levels were significantly (P<0.05) higher than in the normal lactating states.