Efficacy of biotechnologically derived product in counteracting ill effects of aflatoxins in broiler chicken

A preliminary in-vitro aflatoxin adsorption study was conducted, and it was found that, the degradability of aflatoxin (AF) by the biotechnologically derived product (BTP) was similar to that of hydrated sodium calcium allumino-sillicate (HSCAS) and mannan ologosachharide (MOS). Further, an in-vivo trial was undertaken to assess BTP over HSCAS in broiler chicken fed diet containing aflatoxin (AF) with experimental design: T1-basal diet; T₂-250 ppb of AF; T₃-AF 250 ppb with HSCAS at 1 kg/ton; T₄ and T₅-AF 250 ppb with BTP 200 g/ton and 400 g/ton, respectively. During 42 days, trial revealed non-significant differences in performance parameters, dressing percentage, relative organ weights and serum biochemical parameters among treatments. Whereas, serum profile of ALT (P<0.01) and AST (P<0.05) was significantly increased with addition of AF (T₂) indicating limitation of toxicity only to cellular level at liver. Addition of BTP was found to normalize the increased ALT and AST levels.