Central Sheep and Wool Research Institute, Avikanagar-304 501, India
*Corresponding author's e-mail; drcdvet17@gmail.com. Address: Division of Animal Genetics and Breeding, CSWRI, Aviakanagar, Malpura Via; Jaipur, Rajasthan-304501
Online published on 30 April, 2016.
Ovine MHC DRB1 exon 2 (Ovar-DRB1.2) gene is arguably one of the critical genes, responsible for disease resistance against parasite in animals. This study was carried out for indepth analysis of polymorphism in MHC DRB1.2 gene and to explore the underlying molecular mechanisms for the development of disease resistance in Garole. PCR-RFLP study revealed that the gene is polymorphic in nature. The frequency of allele ‘A ’for endonuclease SacI and Allele ‘B ’for endonuclease Hin1I were significantly higher in Garole population.
Ovar DRB1.2, Garole, Nematode Parasites, Disease Resistance, PCR-RFLP
