Indian Journal of Animal Research

A study was conducted to find out the ameliorating effect of dietary Mycosorb (esterified glucomannan, EGM) in experimental aflatoxicosis of broilers. For this purpose 270 number of day-old Anak 2000 chicks were procured and divided into 6 equal treatment groups. A control ration (T₀) was prepared with conventional feedstuffs and an experimental diet (Tx) was prepared from this ration after incorporating aflatoxin (AF) @ 300 ppb produced on rice using Aspergillus flavus: NRRL 2999 strain through fermentation technology. From T_x three rations were prepared by mixing Mycosorb @0.025 per cent of feed (T_xM₁), 0.50 per cent of feed (T_xM₂) or 0.10 per cent of feed (T_xM₃). A positive control diet (T₀M₂) was prepared by mixing Mycosorb @ 0.5 per cent in the control ration. All 6 diets were fed to the respective groups for a period 42 days. Significantly (P<0.05) reduced level of serum cholesterol and serum protein levels were observed in aflatoxin-alone fed group; whereas increase surge of glucose, triglyceride and activities of serum enzymes viz., serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase were recorded in the aflatoxin-alone fed group. However, the increased parameters were corrected to normalcy when Mycosorb was added in the contaminated diet, particularly at 0.1 per cent level. The study showed an ameliorating effect of dietary Mycosorb during experimental aflatoxicosis.