Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2021
  • Volume: 55
  • Issue: 12

Immunohistochemical Changes of Liver Fasciolosis in Cattle and Sheep in Jeddah, Saudi Arabia

  • Author:
  • Muslimah Alsulami1, Khalil Mohamed2
  • Total Page Count: 7
  • Page Number: 1484 to 1490

1Department of Biology, College of Science, University of Jeddah, Jeddah, Saudi Arabia.

2Department of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Saudi Arabia

*Corresponding Author: Khalil Mohamed, Department of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Saudi Arabia. Email: khali72@gmail.com

Online published on 24 January, 2022.

Abstract

Fasciolosis is a crucial helminthes disease caused by two trematodes of the genus Fasciola: Fasciola hepatica (temperate liver fluke) and Fasciolagigantica (tropical liver fluke).

A cross-sectional study was conducted on cattle and sheep in aslaughterhouse todetect animals infected with Fasciolosis. Liver samples were collected from infected animals and transferred to the laboratory for histopathological and immunohistochemical examinations.

Microscopically, the liver sections were showed extensive fibrous connective tissue surrounding the central vein and portal area with extensive thickening of bile ducts wall and fibrosis. Marked infiltration of inflammatory cells wasalso seen.

Keywords

Biliary cirrhosis, Fasciolosis, Histopathological, Immunohistochemical