1Department of Veterinary Pharmacology and Toxicology, Veterinary College, Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar-585 401, Karnataka, India
2Department of Veterinary Pharmacology and Toxicology, College of Veterinary Sciences, PV Narasimha Rao Telangana Veterinary University, Rajendranagar, Hyderabad-500 048, Telangana, India
3Department of Veterinary Pharmacology and Toxicology, Veterinary College Shivamogga, Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar-527 001, Karnataka, India
4Department of Avian Health, ICAR Directorate of Poultry Research, Hyderabad-500 048, Telangana, India
*Corresponding Author: Vijaykumar Matham, Department of Veterinary Pharmacology and Toxicology, Veterinary College, Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar-585 401, Karnataka, India, Email: vijaymatham@gmail.com
Online Published on 10 November, 2022.
Mycoplasma synoviale (Ms), the smallest and simplest bacteria, is categorized as an atypical organism that lacks cell wall. It is a worldwide economically important pathogen of poultry, causing respiratory affections, synovitis, abnormalities in eggshell and drop in production in chickens and turkeys. The present study was conducted to evaluate the druggability targets of Mycoplasma synoviae on cytokines and antioxidant changes in commercial broilers.
Two hundred and eighty, day-old, unsexed broiler chicks of strain Vencobb were randomly allotted to 7 treatment groups with each treatment having 4 replicates and each replicate consisting of 10 birds. Cytokines and antioxidant parameters were determined.
Cytokines, TBARS, SOD, catalase and GSH levels showed a significant (P<0.05) difference between various treatment groups. Therefore, it is necessary to havea regular survey on poultry pathogenic mycoplasmas and to monitor antimicrobial susceptibility patterns in order to ensure that effective chemotherapy is being used to treat mycoplasmal infections.
Antioxidants, Chicken, Cytokines, Mycoplasma, TBARS
