1Department of Physiology and Biochemistry, College of Veterinary Science and Animal Husbandry, Anjora, Durg-491 001, Chhattisgarh, India
2Veterinary Microbiology, College of Veterinary Science and Animal Husbandry, Anjora, Durg-491 001, Chhattisgarh, India
3Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Anjora, Durg-491001, Chhattisgarh, India
*Corresponding Author: M. Roy, Department of Physiology and Biochemistry, College of Veterinary Science and Animal Husbandry, Anjora, Durg-491 001, Chhattisgarh, India, Email: drmanjuroy117@gmail.com
Online Published on 15 July, 2022.
Diabetes mellitus is a complex chronic condition that results in hyperglycemic environment affecting the metabolism of proteins and lipids, promotes inflammation and delays wound healing.
A total of n=30 Wistar rats of either sex were divided into five groups with 6 animals in each. Diabetes mellitus was induced using streptozotocin @ 35 mg/kg body weight and excision wound model was developed in all the animals. Group I and Group II were considered as healthy and diabetic control group respectively. The wounds of Group III, IV and V were treated with topical application of Carica papaya synthesized silver nanoparticles @ 62.5 |jg/ml, Carica papaya leafextract @ 31.25 mg/ml and 10% povidone iodine respectively.
Present study concluded that the characteristics of silver nanaoparticles synthesized form C. papaya leaf extract make them suitable for the treatment of wound healing in diabetic subjects.
Diabetes, Extract, Nanoparticles, Plant, Silver, Wound
