Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2023
  • Volume: 57
  • Issue: 10

Crimean-congo hemorrhagic fever virus infection in domestic ruminants in van province, a non-endemic region in Turkey

  • Author:
  • A.R. Babaoglu1,*, F. Ertas Oguz2, O. Orunc Kilinc3, N. Cetin4, L. Aslan5
  • Total Page Count: 6
  • Page Number: 1358 to 1363

1Department of Virology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van-65080, Turkey

2Tuzluca Vocational School, Igdir University, Igdir-76000, Turkey

3Ozalp Vocational School, Van Yuzuncu Yil University, Van-65080, Turkey

4Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van-65080, Turkey

5Department of Surgery, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van-65080, Turkey

*Corresponding Author: A.R. Babaoglu, Department of Virology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van-65080, Turkey, Email: arbabaoglu@yyu.edu.tr

Online published on 4 November, 2023.

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease of humans that is most widespread in Africa, Asia, the Middle East and Southeast Europe. The disease has continued to be a health problem in Turkey and other endemic countries in recent years. CCHF virus does not cause clinical disease in animal hosts but develops an antibody response and a transient viraemia. The aim of this study is to evaluate the status of CCHF infection serologically and virologically in livestock in the Van region, a non-endemic area in Turkey.

A total of 491 whole blood and 491 serum specimens were collected from cattle, sheep and goats in different locations of Van province in Turkey from May 2020 to October 2021. To determine the CCHFV-specific antibody, all sera from animals were tested with a double-Ag ELISA-Ab kit. An RT-PCR assay was performed on total leucocyte samples for the virological study to detect the presence of European lineage-1 CCHFV nucleic acids and viraemic animals.

The prevalence of CCHFV-specific antibodies in animals was found to be 36.4%. The seroprevalence values detected were 11.6%, 64.45% and 81.63% in cattle, sheep and goats, respectively. In the RT-PCR assay, 1.22% (6/491) of the tested animals were found to be viraemic at the time of sampling.

Keywords

Crimean-congo hemorrhagic fever, ELISA, RT-PCR, Ruminant