1Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College, School of Life Sciences, Yunnan Normal University, China
2Engineering Research Center of Sustinable Development and Utilization of Biomass Energy Ministry of Education, 650500, China
3Key Laboratory of Yunnan Province for Biomass Energy and Environment Biotechnology Kunming, 650500, China
*Corresponding Author: Wan-Long Zhu, Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College, School of Life Sciences, Yunnan Normal University, China, Email: zwl_8307@163.com
Online published on 9 August, 2024.
The ability to respond to global change and coexist with other species depends on phenotypic plasticity and physiological adaptation techniques of the same species living in various places differ according to the region.
Eothenomys miletus from Kunming (KM) and Dali (DL) under fasting and refeeding acclimation, we examined the thermogenic properties and the associated physiological indicators in the AMP dependent protein kinase (AMPK) pathway.
The results demonstrated that energy consumption in E. miletus was decreased by fasting and that the process of survival adaption was significantly influenced by body mass, ghrelin concentration and AMPK activity. Following refeeding, pertinent physiological markers leveled off in the control group, demonstrating the high phenotypic plasticity of E. miletus and the critical role that leptin, ghrelin and AMPK pathways play in energy metabolism and environmental adaption during food fasting. Moreover, there may be a connection between geographical variations in physiological indicators under fasting conditions and variations in the ambient temperature and the food available to E. miletus in various places.
AMPK pathway, Eothenomys miletus, Fasting, Ghrelin, Leptin, Refeeding
