Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2024
  • Volume: 58
  • Issue: 9

Clinico-diagnostic and Therapeutic Management of Ehrlichiosis in Dog

  • Author:
  • P.G. Gamit1, A.R. Patel1, S.A. Mehta1,*, S.V. Mavadiya1, M.D. Patel1, S.M. Parmar2, J.A. Vala2
  • Total Page Count: 7
  • Page Number: 1529 to 1535

1Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Navsari Campus, Navsari-396 450, Gujarat, India

2Clinical Complex, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Navsari Campus, Navsari-396 450, Gujarat, India

*Corresponding Author: S.A. Mehta, Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Navsari Campus, Navsari-396 450, Gujarat, India, Email: samehta@kamdhenuuni.edu.in

Online Published on 14 October, 2024.

Abstract

The research work was undertaken to investigate the efficacy of various diagnostic tests and therapeutic efficacy of different treatment protocols on Canine Monocytic Ehrlichiosis (CME) infected dogs from in and around Navsari, Gujarat, India.

A total of 69 dogs were suspected for ehrlichiosis based on clinical signs and hematological values and further subjected to rapid Ab detection test and PCR assay targeting 16S rRNA gene. The pre and post-treatment haematology and biochemical analysis of treatment groups along with all the healthy dogs were compared. Further, Modified Clinical Sign Grading (MCSG) score for CME-infected dogs was carried out to evaluate therapeutic responses based on minimizing the clinical score.

The hospital based CME incidence was 49.28% among suspected dogs. The anemia along with leucopenia were the most significant hematological alteration recorded while ALP, creatinine and BUN were elevated and albumin was significantly decreased in CME-infected dogs.The significant improvements were observed in haemato-biochemical parameters towards normalcy in both treatment groups. However, a higher percentage of reduction was observed in the clinical score of imidocarb treated CME affected dogs than the oxy-doxycycline therapy after 14 days.

Keywords

Dogs, Ehrlichiosis, Immidocarb, Thrombocytopenia, Treatment