Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2024
  • Volume: 58
  • Issue: 9

Comparison of Biograft (Bovine Small Intestinal Submucosa) and Synthetic Graft (Polypropylene Mesh) Healing Effects when Repairing Abdominal Muscle Defects in Rats

  • Author:
  • S. Ozdemir1,*, A.P. Gokce1, A. Kukner2, G.C. Akbas1, M. Temizel3
  • Total Page Count: 6
  • Page Number: 1550 to 1555

1Department of Surgery, Faculty of Veterinary Medicine, Near East University, Nicosia/TRNC, Turkey

2Department of Histology, Faculty of Medicine, Near East University, Nicosia/TRNC, Turkey

3Experimental Animals and Research Center, Near East University, Nicosia/TRNC, Turkey

*Corresponding Author: S. Ozdemir, Department of Surgery, Faculty of Veterinary Medicine, Near East University, Post Code: 99138, Nicosia/TRNC, Turkey, Email: suleyman.ozdemir@neu.edu.tr

Online Published on 14 October, 2024.

Abstract

Abdominal wall injuries are commonly encountered in veterinary medicine and may lead to significant complications if not appropriately treated. Different types of grafts, including autologous, xenogeneic, biologic or non-biologic and composite grafts, are widely used to ensure adequate tissue repair and prevent recurrence in cases of hernia. However, identifying the most suitable graft for each case is particularly challenging.

In the present study, a commercial graft derived from bovine small intestinal submucosa (bSIS) was compared with the polypropylene mesh (PPM) in terms of their repair efficacy and tissue compatibility. These grafts were used to repair artificially induced abdominal wall defects in 24 rats categorised into two groups. The morphologic and histologic analyses were used to compare and assess the grafts.

The results showed that bSIS has several merits over PPM in terms of biological activity and tissue compatibility.

Keywords

Biograft, Bovine, Hernia, Polypropylene mersilene mesh, Rat, Submucosa