1Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl-796 014, Mizoram, India
2Department of Veterinary Physiology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl-796 014, Mizoram, India
3Department of Veterinary Medicine, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl-796 014, Mizoram, India
*Corresponding Author: Hitesh Bayan, Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl-796 014, Mizoram, India, Email: hbayan@gmail.com
Online Published on 06 February, 2026.
There is no gold standard to evaluate postoperative pain in animals. The study was conducted to evaluate haematobiochemical changes following intraperitoneal bupivacaine and bupivacaine-dexmedetomidine in dogs.
Eighteen clinical cases of dogs requiring laparotomy were randomly divided into three groups viz. Group-B, BD and N comprising of six dogs in each. The animals were premedicated with glycopyrrolate, meloxicam and diazepam. Anaesthetic induction and maintenance was done by using propofol. Intraperitoneally bupivacaine, bupivacaine-dexmedetomidine and normal saline were infused in the three groups. The blood samples were collected prior to pre-medication at 0 min (base line), 30 min (after induction), 2 hrs and 24 hrs interval after intraperitoneal administration of drugs for estimation of haematobiochemical parameters.
The bupivacaine and dexmedetomidine combination reduces the serum glucose and cortisol level which might be indicative of lowered pain response.
Bupivacaine, Dexmedetomidine, Dogs, Intraperitoneal
