Therapeutic intervention of chronic kidney disease associated with multiple complications in a labrador

A 9-year-old male Labrador retriever was presented with a history of weakness, lethargy, inappetence, yellowish urine, and blackish stool. The body temperature was found to be within the normal range (101.1°F) with pale mucous membrane and swelling of the forelimb showing gangrene formation. A blood biochemical test was done in which SGPT, SGOT, BUN, creatine, albumin, glucose, and total protein were significantly higher than the normal range. Abdominal ultrasonography revealed degenerative changes in both the kidneys with significant loss of cortico-medullary junction differentiation, cystitis, hepatomegaly, hepatitis, and ascites were noticed. The overall findings indicated chronic kidney disease with multiple complications. Treatment was initiated with Mannitol (20%), Lasix, Glutamax Forte, Erythropoietin Injection, Renodyl capsule, and other supportive drugs. Blood biochemical tests were done every week for monitoring which showed considerable improvement in the condition of the animal with the ongoing treatment.

• Chronic Kidney Disease (CKD) is one of the most common kidney disorders of adult dogs, especially in male Labradors.

• Proper diagnosis and therapeutic intervention are a must for prolonging the life expectancy of the dogs.

• Prophylactic measures including nutritional management and care are needed to decrease the incidences of CKD in dogs.

• In the present investigation, treatment was given as per standard protocol with few changes based on multiple complications.