Indian Journal of Clinical Anaesthesia
Open Access
  • Year: 2014
  • Volume: 1
  • Issue: 1

Addition of clonidine reduce dose of fentanyl and Ropivacaine in Epidural Anaesthesia

  • Author:
  • Ram Badan Singh1,, Richa Prabhakae1, Rajiv Kumar Dubey1, TB Singh2
  • Total Page Count: 7
  • Page Number: 30 to 36

1Department of anesthesiology, IMS, BHU, Varanasi

2Department of PSM, IMS, BHU, Varanasi

*Corresponding Author: E-mail: rambadan.vns@gmail.com

Online published on 21 March, 2015.

Abstract

To find out effect of clonidine on fentanyl and Ropivacaine requirement to produce Epidural Anesthesia.

After Institute ethical clearance and consent from patient, 60 patients of ASA I and II were studied in 3 groups. All patients were premedicated with ranitidine and metoclopramide. In operation room epidural catheter was placed. After recording base line hemodynamic parameters, drugs were mixed in 20ml syringe according to 3 different groups and given through epidural catheter.

All patients were monitored for hemodynamic changes and recorded at different time interval. Data were analyzed using different tests. Patients of all 3 group have similar level of anesthesia with lower adverse effects hypotension which was more in clonidine, fentanyl and ropivacaine group.

With this study we concluded that adition of clonidine in fentanyl and ropivacaine significantly reduces the amount of ropivacaine and fentanyl required to produce epidural anesthesia.

Keywords

Anesthesia epidural, clonidine, fentanyl, ropivacaine