1Assistant Professor, Dept. of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh
2Associate Professor, Dept. of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh
3Professor, Dept. of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh
4Resident, Dept. of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh
*Corresponding Author: Email: gauravacharyaonline@gmail.com
Online published on 14 June, 2017.
Etomidate is having more stable cardiovascular response as compared to propofol during laryngoscopy and intubation.
The present study compares the effect of propofol and etomidate on cardiovascular response to laryngoscopy and intubation.
This prospective comparative study was conducted at a tertiary care hospital in central India.
Hundred healthy patients of both sex aged between 18 to 45 years, ASA physical status I & II, scheduled for elective surgery under general anaesthesia were selected. Patients in group P (n=48) were induced with propofol 2.5 mg/kg i.v. and group E (n=47) were induced with etomidate 0.3 mg/kg i.v. Patients’ haemodynamic and cardiovascular parameters were recorded before induction (T1), before intubation (T2) and 1, 3, 5 and 10 minutes afterwards. The haemodynamic parameters before induction i.e. T1 was taken as baseline.
The data was collected using Microsoft Excel software and was analysed using SPSS software version17.0.
There was significant difference regarding systolic blood pressure, diastolic blood pressure and mean arterial pressure among two groups. Hypotension was seen in 18.8% patients in group P after induction while there was none in group E.
Etomidate is having more stable cardiovascular response as compared to propofol during laryngoscopy and intubation.
Etomidate, Hypotension, Laryngoscopy propofol
