ndian Journal of Clinical Anaesthesia
  • Year: 2017
  • Volume: 4
  • Issue: 4

Comparative study of caudal Ropivacaine with ropivacaine & Ketamine for postoperative analgesia in paediatric patients

1Assistant Professor, Chettinad Hospital & Research Institute, Kanchipuram

2Professor & HOD, Dept. of Anaesthesia & Critical Care, MGM Medical College & Hospital, Aurangabad, Maharashtra

3Associate Professor, Dept. of Anaesthesia & Critical Care, MGM Medical College & Hospital, Aurangabad, Maharashtra

*Corresponding Author: Email: selvakumar1987@yahoo.com

Online published on 23 February, 2018.

Abstract

Objective of this study was to determine the efficacy of caudal Ketamine added to ropivacaine in providing postoperative analgesia in pediatric age group.

This was a prospective randomized double blind study carried out in 60 ASA grades I/II children (29years) posted for below umbilical surgeries over a period of 2 years. They were randomized into two groups of 30 each. Group A received caudal ropivacaine 0.25% (1ml/kg) & Group B received caudal ropivacaine 0.25% (1ml/kg) with Ketamine (0.5mg/kg). The parameters studied were intraoperative hemodynamic changes, duration of postoperative analgesia and incidence of complications.

The mean duration of post-operative analgesia was significantly higher in Group B (395.26±55.97 minutes) than in group A (217.66±30.42 minutes), p = 0.000. The perioperative hemodynamic parameters were stable and comparable in both the groups. Incidence of vomiting in group A was 6.6% and 10% in group B, the difference being statistically insignificant. None of the patients in both the groups had bradycardia, hypotension and delirium.

The present study demonstrated that caudal administration of ropivacaine 0.25% (1 ml/kg) with Ketamine (0.5 mg/kg) results in longer duration of analgesia compared with 0.25% ropivacaine (1 ml/kg) alone, without any significant sideeffects.

Keywords

Caudal Analgesia, Ketamine, Ropivacaine