1Associate Professor, Dept. of Anaesthesia and Critical Care, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
2Professor & HOD, Dept. of Anaesthesia and Critical Care, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
*Corresponding Author: Email: dhanashreedongare@gmail.com.
Online published on 24 September, 2018.
Functional endoscopic sinus surgery (FESS) requires good intraoperative surgical field visualization for better identification of structures. Among the many modalities for improving visibility, antifibrinolytic agent like Tranexamic acid has shown good results in many other surgeries. In this study, we have evaluated the effect of a single bolus dose of 15mg/kg intravenous Tranexamic acid when used as an adjunct.
We have studied group T (n=30), who received Inj. Tranexamic acid against group C (n=30) i.e. control group. They were compared for surgical field using Boezaart scale, surgical duration and blood loss. Statistical analysis was done by unpaired t test and chi square test as was appropriate.
T group showed significantly lower values of Boezaart scale score i.e. better visualisation for surgical field (p<0.001). Blood loss was also less in T group (103±23.97 ml) as against group C (150±62.33 ml). The duration of surgery was 53.83 ±8.57 minutes in group T and 62.3±11.8 minutes in group C. Both the differences were statistically significant.
We found that Tranexamic acid has a beneficial role in functional endoscopic sinus surgeries by improving the quality of surgical field when used as an adjunct.
Tranexamic acid, surgical field, functional endoscopic sinus surgery
