1Post Graduate Student, Dept. of Biochemistry, SCB Medical College & Hospital, Cuttack
2Prof. & HOD, Dept. of Biochemistry, SCB Medical College & Hospital, Cuttack
3Associate Professor, Dept. of Biochemistry, SCB Medical College & Hospital, Cuttack
4Associate Professor, Dept. of Medicine, SCB Medical College & Hospital, Cuttack
*Corresponding Author E-mail: arinmck@gmail.com
Online published on 4 February, 2016.
The effectiveness of cystatin C as a biomarker in acute hemorrhagic/ischemic stroke is being studied recently. It is due to accumulating evidence indicating a link between vascular disease of the kidney and brain. In this study we have investigated the association of serum cystatin C with first onset acute stroke.
A total of 45 patients with first onset stroke, aged more than 30 years, were selected for the study based on history, detailed clinical examinations, neuro-imaging and other related investigations. The patients were presenting within 72 hours after onset of symptoms.
Serum cystatin C levels were significantly elevated (p<0.0001) in cases (1.60±0.88 mg/l) when compared with controls (0.82±0.11 mg/l). Serum creatinine levels were also significantly elevated (p<0.001) in cases (1.77±1.23 mg/dl) when compared with controls (1.05±0.18 mg/dl). Among lipid profile parameters, total cholesterol, triglycerides, LDL and VLDL cholesterol were all significantly increased in cases when compared with controls.
Acute stroke, Cystatin C, Dyslipidemia, Electrolytes
