1Assistant Professor, Sree Balaji Medical College & Hospital, Chromepet, Chennai
2Associate Professor, ESIC Medical College and PGIMSR, KK Nagar, Chennai
*Corresponding Author: E-mail: maya.anusha@gmail.com
Online published on 22 June, 2016.
Neutrophil Gelatinase Associated Lipocalin NGAL predicts Acute Kidney Injury earlier than creatinine in cardiac surgery patients. This study aims at understanding the correlation between the two biomarkers.
53 patients who underwent major cardiac surgery were included in the study. Venous blood samples were collected before surgery and at 4 hours after surgery to estimate plasma NGAL and before surgery, at 4 hours, 24 hours, 48 hours and 72 hours after surgery from the patients to estimate serum creatinine. Correlation analysis was done between NGAL and creatinine using Pearson Correlation Coefficient.
The correlation coefficients for plasma NGAL values at 4 hours after surgery with the serum creatinine values were r = 0.87 at 4 hours, r = 0.86 at 24 hours, r = 0.91 at 48 hours and r = 0.87 at 72 hours after surgery.
The correlation coefficient values shows that plasma NGAL values at 4 hours after surgery were highly correlated with the serum creatinine values at 4 hours, 24 hours, 48 hours and 72 hours after surgery.
This study shows that NGAL values are highly correlated with creatinine values.
NGAL, Creatinine, Aki, Cardiac Surgery
