1PG Student, Dept. of Biochemistry, Subharti Medical College, Meerut, Uttar Pradesh
2Assistant Professor, Dept. of Biochemistry, Subharti Medical College, Meerut, Uttar Pradesh
3Professor & Head, Dept. of Biochemistry, Subharti Medical College, Meerut, Uttar Pradesh
Pre-eclampsia (PE) is defined as the new onset of hypertension and proteinuria during the second half of pregnancy. In the Indian scenario, it accounts for 44.44% of all cases of hypertensive disorders of pregnancy. Microalbuminuria is one the classic signs of pre-eclampsia.
The aim of the study was to determine microalbuminuria as predictor of pre-eclampsia.
A total of 145 pregnant women in their second trimester of pregnancy were included in the study. From all these subjects, clean catch morning urine sample (5ml) was collected in a sterile container. Urinary Creatinine and urinary microalbumin was estimated by kit based method on Vitros Fusion 5.1 FS fully automated analyzer from Ortho Clinical Diagnostic USA. The statistical significance of difference between mean values was assessed by Student's unpaired t-test.
Pregnant women who developed pre-eclamsia were having significantly higher micro albumin level and Albumin Creatinine Ratio as compared to normotensive pregnant women.
To determine microalbuminuria as predictor of pre-eclampsia, further detailed study is required in large group of population.
Pre-eclampsia, Microalbuminuria, Albumin Creatinine Ratio, BP, Pregnancy
