International Journal of Clinical Biochemistry and Research
  • Year: 2016
  • Volume: 3
  • Issue: 4

Significance of hs-CRP in vestibular dysfunction in type II diabetes mellitus

1Dept. of Biochemistry, Sree Balaji Medical College & Hospital, Chennai, Tamil Nadu

2Dept. of ENT, Sree Balaji Medical College & Hospital, Chennai, Tamil Nadu

3Dept. of Community Medicine, Sree Balaji Medical College & Hospital, Chennai, Tamil Nadu

*Corresponding Author: Email: doraisaravanan@yahoo.co.in

Online published on 14 June, 2017.

Abstract

The most common morbid complication of Type-2 diabetes mellitus is vestibulopathy. Microangiopathy & Oxidative stress due to diabetes mellitus is one of the causative factor of this vestibular dysfunction.

The aim of the study is to find the significance of hs-CRP in vestibular dysfunction in type 2 diabetes mellitus.

A cross-sectional study of 100 diabetic patients were tested for vestibular function by electronystagmography. Clausen butterfly chart is generated based on the bithermal caloric stimulation and the code is ascertained & Serum hsCRP was estimated for these patients by immunoturbidometry. Data analysis done using SPSS package.

65% of diabetic population with hsCRP>3mg/L had vestibular dysfunction which is significant. It is also found that 70% of diabetic patients with greater than 4 years duration had vestibular dysfunction

From this study it is concluded that the proportion of diabetic vestibulopathy is higher in those having hsCRP of >3mg/L. So it is advisable to do screening for all diabetics by estimating hsCRP & vestibular dysfunction particularly those having hsCRP >3mg/L so as to prevent the morbid complication diabetic vestibulopathy.

Keywords

Diabetic Vestibulopathy, Electronystagmography, hsCRP, Clausen butterfly chart